Dr. Frade studied at the Complutense University of Madrid, where he graduated in Biological Sciences in 1989. He later obtained his PhD in Sciences from the Autonomous University of Madrid in 1994. Between 1996 and 1998 he worked in Germany in the Department of Neurobiochemistry at the Max-Planck Institute for Neurobiology. During this period he carried out studies on the induction of apoptosis mediated by the interaction of NGF with its p75NTR receptor that were published in the scientific journal Nature. After he joined the Cajal Institute in 1998, Dr. Frade leads a research group that studies the mechanisms involved in the activation of the cell cycle in neurons and neuronal tetraploidization in the brain. As Scientific Director of Tetraneuron, José María provides the necessary scientific rigor for the development of our pipeline of therapies against neurodegenerative diseases.